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La Jolla Pharma Discovers Molecule That Produces Positive Results

Company scientists have generated highly selective inhibitors of SSAO (semicarbazide-sensitive amine oxidase), an enzyme that has been implicated in inflammatory responses in many tissues and organs. Preclinical studies in animal models of multiple sclerosis, rheumatoid arthritis and acute inflammation have shown that treatment with the Company's inhibitors both maintained function and reduced disease activity compared with placebo treatment.

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December 3, 2003 in research | Permalink